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Ultimate Southern Chicken Spaghetti Casserole Recipe to Warm Your Soul - Featured Image

Ultimate Southern Chicken Spaghetti Casserole Recipe to Warm Your Soul

Learn how to make delicious Southern Chicken Spaghetti Casserole. Easy recipe with step-by-step instructions.

  • Total Time: 45 minutes
  • Yield: 4 servings 1x

Ingredients

Scale

The key to this dish lies in selecting the right ingredients that bring both flavor and heartiness without fuss. I always choose fresh chicken breasts and quality spaghetti to ensure a comforting texture. The creamy sauce gets its richness from a blend of cheeses and cream, and I love adding bell peppers and onions for a little extra warmth and color. When shopping, I keep an eye out for simple, fresh ingredients that don’t require complicated prep—because I know how much time we all save that way.

  • 3 cups cooked spaghetti (about 8 ounces dry)
  • 2 cups cooked, shredded chicken breast
  • 1 cup diced bell peppers (red or green)
  • 1/2 cup diced onion
  • 2 cloves garlic, minced
  • 1 can (10.5 oz) cream of mushroom soup
  • 1 can (10.5 oz) cream of chicken soup
  • 1 cup sour cream
  • 2 cups shredded cheddar cheese, divided
  • 1/2 cup grated Parmesan cheese
  • 1/2 teaspoon black pepper
  • 1/2 teaspoon smoked paprika (optional for a little smoky depth)
  • 1 tablespoon olive oil or butter for sautéing

Substitutions: If you prefer, you can swap sour cream for Greek yogurt for a lighter option, or use rotisserie chicken to save time. For a dairy-free version, try coconut cream and a vegan cheese alternative.

Instructions

  1. Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish.
  2. Cook spaghetti according to package instructions until al dente. Drain and set aside.
  3. In a large skillet, heat olive oil or butter over medium heat. Add diced onions and bell peppers, sautéing until soft and fragrant—about 5 minutes. Add minced garlic and cook for another minute.
  4. In a large mixing bowl, combine the cooked spaghetti, shredded chicken, sautéed vegetables, cream of mushroom soup, cream of chicken soup, sour cream, 1 cup of cheddar cheese, Parmesan cheese, black pepper, and smoked paprika if using. Stir gently until everything is well mixed.
  5. Transfer the mixture to the prepared baking dish. Sprinkle the remaining cheddar cheese evenly over the top.
  6. Bake uncovered for 25-30 minutes, or until the casserole is bubbly and the cheese is golden and melted.
  7. Remove from the oven and let it rest for 5 minutes before serving to allow the flavors to settle.

  • Author: Jenny
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Main Dish
  • Method: Cooking
  • Cuisine: International

Keywords: Southern Chicken Spaghetti Casserole, recipe, cooking, food